October 03, 2022
Chronic Pain Research, with special guest Jason Busse
In this episode, Mo and Marc are joined by special guest Jason Busse (Professor in the Department of Anesthesia at McMaster University, Director of the National Pain Centre, and Associate Director of the Michael G. DeGroote Centre for Medicinal Cannabis Research), in a discussion on research into the relative effectiveness and harms associated with various types of opioids, cannabinoids, and psychedelics in the treatment of chronic pain. Links: Noori A, Sadeghirad B, Wang L, Siemieniuk RAC, Shokoohi M, Kum E, Jeddi M, Montoya L, Hong PJ, Zhou E, Couban RJ, Juurlink DN, Thabane L, Bhandari M, Guyatt GH, Busse JW. Comparative benefits and harms of individual opioids for chronic non-cancer pain: a systematic review and network meta-analysis of randomised trials. Br J Anaesth. 2022 Sep;129(3):394-406. doi: 10.1016/j.bja.2022.05.031. Epub 2022 Jul 9. PMID: 35817616. https://bit.ly/3KOtVat Kane RL, Bershadsky B, Rockwood T, Saleh K, Islam NC. Visual Analog Scale pain reporting was standardized. J Clin Epidemiol. 2005 Jun;58(6):618-23. doi: 10.1016/j.jclinepi.2004.11.017. PMID: 15878476. https://bit.ly/3BrSIyd Busse JW, Craigie S, Juurlink DN, Buckley DN, Wang L, Couban RJ, Agoritsas T, Akl EA, Carrasco-Labra A, Cooper L, Cull C, da Costa BR, Frank JW, Grant G, Iorio A, Persaud N, Stern S, Tugwell P, Vandvik PO, Guyatt GH. Guideline for opioid therapy and chronic noncancer pain. CMAJ. 2017 May 8;189(18):E659-E666. doi: 10.1503/cmaj.170363. PMID: 28483845; PMCID: PMC5422149. https://bit.ly/3QhqY3f Subspecialties: Basic Science Education and Training Ethics Foot & Ankle Hand & Wrist Hip Knee Oncology Orthopaedic Essentials Pain Management Rehabilitation Pediatrics Spine Shoulder Elbow Sports Medicine Trauma ...
September 19, 2022
Hot Topics in Orthopaedics: (1) Predicting the Future with Evidence from the Past and (2) Large Administrative Database Research
In this episode, Mo and Marc discuss 2 recent OE and JBJS articles that caught their eye. The first part of the discussion focuses on how orthopaedists can forecast the future with evidence from the past, and the second part focuses on the challenges and appropriate applications of large administrative database research. Links: Phillips S and Bhandari M. Predicting the Future with Evidence from the Past: The OE Forecaster. OE Insights. August 19, 2022. Article no. 103. https://myorthoevidence.com/Insight/Show/138 Fujiwara T, Ogura K, Alaqeel M, Healey JH. Geographic Access to High-Volume Care Providers and Survival in Patients with Bone Sarcomas: Nationwide Patterns in the United States. J Bone Joint Surg Am. 2022 Aug 17;104(16):1426-1437. doi: 10.2106/JBJS.21.01140. Epub 2022 Jun 21. PMID: 35730765. https://bit.ly/3CKlElY Subspecialties: Oncology Orthopaedic Essentials Sports Medicine Trauma ...
September 05, 2022
Major Extremity Trauma and Rehabilitation Consortium (METRC) and War Injury Research, with special guests Matt Schmitz and Patrick Osborn
In this episode, Marc and Mo are joined by special guests Matt Schmitz (JBJS Deputy Editor for Social Media; San Antonio Military Medical Center; Uniformed Services University of the Health Sciences; Brooke Army Medical Center) and Patrick Osborn (Brooke Army Medical Center; Baptist Health System) in a discussion on the research being done by the Major Extremity Trauma and Rehabilitation Consortium (METRC) and how the knowledge gained has impacted the ability of the orthopaedic surgeon to treat the injured warrior. Links: Major Extremity Trauma Research Consortium (METRC). Outcomes Following Severe Distal Tibial, Ankle, and/or Mid/Hindfoot Trauma: Comparison of Limb Salvage and Transtibial Amputation (OUTLET). J Bone Joint Surg Am. 2021 Sep 1;103(17):1588-1597. doi: 10.2106/JBJS.20.01320. PMID: 33979309. https://bit.ly/3QOCd4a Major Extremity Trauma Research Consortium (METRC). Effect of Intrawound Vancomycin Powder in Operatively Treated High-risk Tibia Fractures: A Randomized Clinical Trial. JAMA Surg. 2021 May 1;156(5):e207259. doi: 10.1001/jamasurg.2020.7259. Epub 2021 May 12. PMID: 33760010. https://bit.ly/3cirkso Subspecialties: Trauma Rehabilitation ...
August 22, 2022
Hot Topics in Orthopaedics: Oxygen and Ozone
In this episode, Marc and Mo discuss 2 recent JBJS and OE articles that caught their eye. The first part of the discussion focuses on a large RCT evaluating the effect of supplemental perioperative oxygen on SSI among adults with lower-extremity fractures, and the second part focuses on a systematic review on the use of medical ozone versus hyaluronic acid for knee OA. Links: Major Extremity Trauma Research Consortium (METRC). Effect of Supplemental Perioperative Oxygen on SSI Among Adults with Lower-Extremity Fractures at Increased Risk for Infection: A Randomized Clinical Trial. J Bone Joint Surg Am. 2022 Jul 20;104(14):1236-1243. doi: 10.2106/JBJS.21.01317. Epub 2022 May 11. PMID: 35775284. https://bit.ly/3Q2hPvF Intra-Articular Injection of Medical Ozone Versus Hyaluronic Acid for Knee Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. OE Original. 2022;5(5):3. Available from: https://myorthoevidence.com/Blog/Show/183 Subspecialties: Infection Knee Orthopaedic Essentials Trauma ...
August 08, 2022
Physician Etiquette and Attire (with Special Guests Elizabeth Arendt and Herman Johal)
In this episode, Marc and Mo are joined by special guests Elizabeth Arendt (Professor and Vice-Chair, Department of Orthopedic Surgery, University of Minnesota) and Herman Johal (Assistant Professor, Department of Surgery, McMaster University) in a lively discussion of the evolution of physician attire (neckties, white coats, blazers, dresses, footwear, T-shirts, shorts, scrubs, zip-ups, etc.) and its role in projecting professionalism and authority, connecting with patients, and training residents. Links: Petrilli CM, Saint S, Jennings JJ, et al. Understanding patient preference for physician attire: a cross-sectional observational study of 10 academic medical centres in the USABMJ Open 2018;8:e021239. doi: 10.1136/bmjopen-2017-021239. https://bit.ly/3Bnyw0N Subspecialties: Orthopaedic Essentials ...
July 25, 2022
Hot Topics: (1) The Importance of Blinded Assessment of Outcomes in Clinical trials (2) TXA in Hip Fractures
In this episode, Marc and Mo discuss 3 recent articles that caught their eye. The first part of the discussion focuses on the importance of blinded assessment of outcomes in clinical trials, and the second part focuses on the use of tranexamic acid in patients with hip fractures. Links: Metcalfe A, Parsons H, Parsons N, Brown J, Fox J, Gemperlé Mannion E, Haque A, Hutchinson C, Kearney R, Khan I, Lawrence T, Mason J, Stallard N, Underwood M, Drew S; START:REACTS team. Subacromial balloon spacer for irreparable rotator cuff tears of the shoulder (START:REACTS): a group-sequential, double-blind, multicentre randomised controlled trial. Lancet. 2022 May 21;399(10339):1954-1963. doi: 10.1016/S0140-6736(22)00652-3. Epub 2022 Apr 21. PMID: 35461618. https://bit.ly/3P62z0I Verma N, Srikumaran U, Roden CM, Rogusky EJ, Lapner P, Neill H, Abboud JA; SPACE GROUP. InSpace Implant Compared with Partial Repair for the Treatment of Full-Thickness Massive Rotator Cuff Tears: A Multicenter, Single-Blinded, Randomized Controlled Trial. J Bone Joint Surg Am. 2022 Apr 22. doi: 10.2106/JBJS.21.00667. Epub ahead of print. PMID: 35777921. https://bit.ly/3cBTmz6 Porter SB, Spaulding AC, Duncan CM, Wilke BK, Pagnano MW, Abdel MP. Tranexamic Acid Was Not Associated with Increased Complications in High-Risk Patients with Intertrochanteric Fracture. J Bone Joint Surg Am. 2022 Jul 6;104(13):1138-1147. doi: 10.2106/JBJS.21.01389. Epub 2022 Apr 29. PMID: 35775092. https://bit.ly/3AHrhjT POISE Study Group, Devereaux PJ, Yang H, Yusuf S, Guyatt G, Leslie K, Villar JC, Xavier D, Chrolavicius S, Greenspan L, Pogue J, Pais P, Liu L, Xu S, Málaga G, Avezum A, Chan M, Montori VM, Jacka M, Choi P. Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial. Lancet. 2008 May 31;371(9627):1839-47. doi: 10.1016/S0140-6736(08)60601-7. ...